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EDCTP2 : SIMBLE

Full Name: Simplified Blood Culture System

Duration: 1/7/2021-31/12/2024

Partners:

  • Institute of Tropical Medicine (ITM), Belgium
  • Université Libre de Bruxelles (ULB), Belgium
  • Commissariat à l'Energie Atomique et aux Energies Alternatives (CEA), France
  • Reactivos Para Diagnóstico (RPD), Spain
  • Centre National Hospitalier Universitaire de Pneumo-Phtisiologie (CNHU-PPC), Benin
  • Centre Hospitalier Universitaire Yalgado Ouédraogo (CHUYO), Burkina Faso

Objective:

  • The SIMBLE project is designed to evaluate Bactinsight, our recently developed simplified blood culture system, which consists of two modules:
  • A portable measurement device (turbidity metre) which detects bacterial growth in blood culture bottles, based on the turbidity of the culture medium
  • Blood culture bottles with optimised formulation
  • An additional module on the Bactinsight system contains a lens-free microscope, which simplifies and expedites the identification of the causative organisms. Bactinsight will be evaluated across two field sites in Western Africa by comparing it to the reference systems already in use. In addition, we will evaluate the usability, acceptability, adoptability and performance of the system.
  • The Bactinsight blood culture bottles will be produced on-site in Benin, in a production container production facility that will be installed on the Cotonou campus at the start of the project. With this production facility, we want to enforce local production not only during the SIMBLE study, but also after.

INTEC's Role:

  • Design turbidity metre.

Project Web site: https://www.itg.be/en/research/projects/simplified-blood-culture-system-simble

People involved